What are the reasons for changing the profile of cancer incidence in the population of North-Eastern Siberia over the past 100 years (for example, Yakutia)?


Tikhonov D.G., Ivanov P.M.


Annotation. The structure of the oncological incidence among the population of Yakutia has changed significantly over the past 100 years. During this period, esophageal and gastric cancers lost the leading positions in the structure of oncological pathology; there was a sharp upsurge in the number of lung cancer and its decline by the end of the analyzed period; there has been a rise in the number of malignant neoplasms of the reproductive organs and large intestine. It should be noted that a sharp decrease in the number of esophageal cancer among the region’s population was due not to only the improvement of socio-economic conditions, but also to the well-coordinated and focused work of practical healthcare coordinated by the research team of Professor Ara Bezrodnykh that focused on the early diagnosis and prevention of malignant neoplasms of the upper digestive tract. The early 21st century was characterized by the beginning of the formation of the structure of oncological morbidity connected with the post-industrial development in Yakutia. The reasons for the recent changes are still being analyzed to be clarified.

Key words: Northeast Siberia, Yakutia, incidence, cancer of the esophagus, cancer of the stomach, lung cancer, cancer of the reproductive organs, morbidity dynamics over 100 years.

For citations: Tikhonov D.G., Ivanov P.M. What are the reasons for changing the profile of cancer incidence among the population of Northeastern Siberia over the past 100 years (for example Yakutia)? // Siberian Research. 2019. 2(2). P. 5 – 11.

Received December 10, 2018, accepted for publication November 12, 2019, published December 1, 2019.


About the authors

TIKHONOV Dmitrii Gavrilievich, MD, PhD, Professor, Senior Research Officer of the Scientific Research Center of the Medical Institute of the Northeast Federal University, 677000, Yakutsk, St. Builders 8, Russia,, e-mail:

IVANOV Petr Mikhailovich, DM, PhD, Professor, Head of the oncology course of the department of faculty surgery of the Medical Institute of the North-Eastern Federal University, 677000, Yakutsk, St. Belinsky, 58, Russia, e-mail:



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