Damage to the digestive tract in COVID-19, cause or consequence. Will an oral vaccine be effective?

 

 

Tikhonov D.G., Vladimirtsev V.A.

 

 

 

Annotation. Analysis of the pathways of the virus infiltration, the features of digestive lesions in COVID-19 and the search for an answer to the dilemma: Is the digestive system affected by this viral infection the cause or consequence? - allowed us to formulate a hypothesis about the possibility of developing a safe and effective oral vaccine against SARS-Cov-2. This paper substantiated the hypothesis. In our opinion, the oral vaccine against SARS-Cov-2 is likely to be the safest, even with the use of an attenuated strain of the virus.

 

Key words: SARS-Cov-2, COVID-19, digestive tract, oral vaccine

 

For citations: Tikhonov D.G., Vladimirtsev V.A. Damage to the digestive tract in COVID-19, cause or consequence. Will an oral vaccine be effective? // Siberian Research. 2020/ 4(4). P. http://doi.org/10.33384/26587270.2020.04.02.07e

 

Received 09, September 2020; accepted for publication 13, December; published 15, December.

 

 

http://doi.org/10.33384/26587270.2020.04.02.07e

 

 

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About the authors

 

TIKHONOV Dmitry Gavrilievich, MD, Professor, Senior Research Officer of the Scientific research Center of the Medical Institute of the North-Eastern Federal University, 677009, Yakutsk, St. Bld. 8, Russia, https://orcid.org/0000-0003-3385-9471, e-mail: Tikhonov.dmitri@yandex.ru.

 

VLADIMIRTSEV Vsevolod A., PhD Russia, https://orcid.org/0000-0002-5480-3592, e-mail: sevelot@mail.ru.

 

 

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Dear Readers! The views expressed in this Journal are those of the author and do not necessarily reflect the views of the editorial staff.